Klonopin – the most effective drug to treat anxiety.
Klonopin is a sedative-hypnotic, connected to the class of benzodiazepines. It has an enhanced sedative effect, which while consumed in standard dosages does not have an anxiolytic, muscle relaxant, and anticonvulsant effects.
- Drug Name: Klonopin (Clonazepam)
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Klonopin reduces the anxiety as they have the tendency to decrease the intensity of pain when taken by the patient in normal dosages. Ricochet insomnia might cause while quitting the use of clonazepam after regular usage. Benzodiazepines could lead to getting worse depression. Overdosing indications can lead to extreme confusion, drowsiness, fainting, and muscle weakness.
Symptoms for usage of Klonopin
Seizures and panic disorders: A few consumers report hangover-like indications of drowsiness, headaches, sluggishness, and irritability upon getting up from sleep when the drug is consumed before going to bed.
Contraindications to the usage of Klonopin
- Acute seizures and/or serious respiratory depression;
- Severe acute or chronic liver failure;
- Night apnea (as well as predictable);
- Children (below the age group of 18 years);
- Increased sensitivity to Clonazepam or other ingredients of the medication.With caution: severe respiratory depression, aggravate hepatic porphyria, depression, alcoholism, drug addiction, and various other habits.
Dosage regimen and method of application of Klonopin
Take in a solitary dosage of 0.5 to 1 mg per day. The treatment began with a dosage of 0.5 mg for aged or weakened patients and those who suffer from an impaired liver function. The dosage can be increased to 1 to 2 mg if essential (inadequate medical effect) and when there is good tolerability of the medication.The maximum everyday dosage of Klonopin is 2 mg. The course of treatment should never exceed above four weeks. The suggested period of treatment with transient seizures is about 2 to 5 day. It may exceed from 2 to 3 weeks in the event of some exceptional cases. The slow withdrawal of the medication is not necessary for very short courses of treatment. The elimination of Clonazepam should be carried out slowly (initially a reduction in the day-to-day dosage, and then the drug withdrawal) in the event of long-term usage of the medication in order to decrease the risk of growth of rebound insomnia.
Generally, Klonopin is well tolerated. The common side effects of having Klonopin include anxiety, poor coordination, and drowsiness. The long-term use of this drug might cause addiction, withdrawal indications, and tolerance if stopped consuming it suddenly. Addiction may cause in one-third of people who consume Klonopin for more than four weeks. It could increase the threat of suicide in people who are depressed. It can cause damage to the newborn infant when used during the period of pregnancy. Klonopin binds with the GABAA receptors and upsurges the effect of the principal inhibitory neurotransmitter, known as the gamma-aminobutyric acid (GABA).
Klonopin may be very effective in controlling the state of epileptic, however, certain potentially severe side-effects like behavior and interference with cognitive functions might develop when consumed for an extended period of time. A lot of persons treated on a long-term basis develop an addiction. Physiological addiction was established by flumazenil-precipitated withdrawal. Consumption of alcohol or any other CNS sedatives while using Klonopin strengthens the side effects of the medication significantly.
The neonatal withdrawal disorder related to Klonopin includes agitation, abnormal sleeping patterns, apnea, bradycardia, cyanosis, diarrhea, growth retardation, hypertonia, hyperreflexia, inconsolable crying, irritability, the risk of aspiration of feeds, suckling difficulties, tremors or jerking of the extremities, and vomiting.
Application in pregnancy and breastfeeding
This medication is contraindicated during the period of pregnancy and breastfeeding. Usage of this drug under these circumstances may cause violations of liver function. It is also contraindicated for patients with acute seizures and hepatic porphyria.
With caution: liver damage of mild to moderate severity may occur. The treatment begins with a dosage of 0.5 mg per day if liver function is compromised. It might even cause harm to the newborn baby when consumed during pregnancy.
The aged users are particularly at risk of the increased possibility of harm from drug accumulating and motor weakening side effects. Klonopin also needs special care when used up by individuals who could be alcohol- or drug-dependent, pregnant, or can have comorbid psychiatric conditions. It is usually not suggested for consumption by aged people even for the treatment purposes because of its high strength compared to other drugs.